Description

tert-Butyl 6-Benzyloxy-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Indole-1-Carboxylate is a high-value, multifunctional indole-based boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical key building block in modern pharmaceutical and agrochemical research, enabling the construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl systems found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex indole scaffolds.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials and advanced polymers.
• Academic & Contract Research: Essential for methodology development and exploring new chemical spaces in medicinal and synthetic chemistry laboratories.
• Process Chemistry: Employed in route scouting and scale-up studies for the efficient production of target molecules.

Basic Information

Product Name	tert-Butyl 6-Benzyloxy-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Indole-1-Carboxylate
CAS No.	2304633-94-9
Molecular Formula	C26H32BNO5
Molecular Weight	449.35 g/mol
Synonyms	6-(Benzyloxy)-1-[(tert-butoxy)carbonyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 1-Boc-6-benzyloxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole; tert-Butyl 6-(benzyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate; 6-Benzyloxy-1-Boc-indole-3-boronic acid pinacol ester; 3-Borono-6-benzyloxy-1H-indole-1-carboxylic acid tert-butyl ester pinacol cyclic ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Benzyloxy-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Indole-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as verified by HPLC, NMR, and MS. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.