Description

1(2H),2'-Bipyridine, 3,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, advanced pharmaceutical intermediate and building block featuring a bipyridine core functionalized with a pinacol boronate ester group. This compound matters for its critical role in modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex, functionalized bipyridine derivatives. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who are developing new active ingredients, ligands, and functional organic materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting complex heterocyclic structures.
• Suzuki-Miyaura Cross-Coupling Reagent: The pinacol boronate ester group makes it an excellent partner for palladium-catalyzed coupling with aryl/heteroaryl halides, facilitating carbon-carbon bond formation.
• Ligand Synthesis: Used to create sophisticated bipyridine-based ligands for catalysis, metal-organic frameworks (MOFs), and coordination chemistry applications.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and herbicides with tailored properties.
• Organic Electronic Materials: A potential monomer or precursor for constructing conjugated polymers and small molecules used in OLEDs, sensors, and other optoelectronic devices.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological systems and interactions.

Basic Information

Item	Details
Product Name	1(2H),2'-Bipyridine, 3,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	2304631-50-1
Molecular Formula	C20H25BN2O2
Molecular Weight	336.24 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-[2,2'-bipyridine]; 4-(Pinacolatoboryl)-3,6-dihydro-2H-[2,2'-bipyridine]; 3,6-Dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-[2,2'-bipyridine]; 4-Boronic acid, 3,6-dihydro-2H-[2,2'-bipyridine]-4-, pinacol ester; 1(2H),2'-Bipyridine, 3,6-dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Bipyridine boronic ester pinacol; Advanced Suzuki coupling building block
EINECS	Contact for details

Quality Control

Our production of 1(2H),2'-Bipyridine, 3,6-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.