Description

1,4-Benzenedicarboxylic Acid, 2,5-Bis[(2R)-2-Hydroxypropoxy]-, 1,4-Dihydrazide is a high-purity, chiral dihydrazide derivative of terephthalic acid, designed for advanced material synthesis. This compound is valued for its ability to act as a specialized linker or cross-linking agent, introducing both hydrazide functionality and chiral centers into polymer backbones. It is primarily utilized by R&D and production teams in the pharmaceutical intermediate, specialty polymer, and advanced adhesive sectors seeking to develop materials with specific stereochemical and mechanical properties.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and drug conjugates requiring precise stereochemistry.
• Specialty Polymer Synthesis: Used as a monomer or cross-linker in the production of polyhydrazides, polyamides, and other high-performance polymers with enhanced thermal stability and mechanical strength.
• Liquid Crystal & OLED Materials: Incorporated into the molecular design of advanced organic electronic materials due to its rigid aromatic core and functionalizable side chains.
• Adhesive & Coating Formulations: Functions as a curing agent or adhesion promoter in high-specification epoxy and polyurethane systems, improving bond strength and chemical resistance.
• Chelating Agent Precursor: Acts as a precursor for ligands used in catalysis and metal ion sequestration applications.
• Academic & Industrial Research: Employed in chemical research for studying structure-property relationships in chiral macromolecules and supramolecular assemblies.

Basic Information

Product Name	1,4-Benzenedicarboxylic Acid, 2,5-Bis[(2R)-2-Hydroxypropoxy]-, 1,4-Dihydrazide
CAS No.	2260914-35-8
Molecular Formula	C16H24N4O6
Molecular Weight	368.39 g/mol
Synonyms	2,5-Bis[(2R)-2-Hydroxypropoxy]terephthalic Dihydrazide; (R,R)-2,5-Bis(2-hydroxypropoxy)terephthalohydrazide; Terephthalic acid, 2,5-bis[(2R)-2-hydroxypropoxy]-, dihydrazide; Chiral Terephthalic Dihydrazide Derivative; (R)-HPOT Hydrazide; 1,4-Dihydrazinyl-2,5-bis[(2R)-2-hydroxypropoxy]benzene; 2,5-Di((R)-2-hydroxypropoxy)-1,4-benzenedicarboxylic acid dihydrazide
EINECS	Contact for details

Quality Control

Our production of 1,4-Benzenedicarboxylic Acid, 2,5-Bis[(2R)-2-Hydroxypropoxy]-, 1,4-Dihydrazide adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) and handle it in a moisture-controlled environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.