Description

2-Oxo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,2-Dihydropyridine-3-Carbonitrile is a high-value, multi-functional chemical building block that combines a pyridone core with a boronic ester pinacol group and a nitrile moiety. This compound matters for its versatility in modern synthetic chemistry, serving as a key intermediate in the construction of complex molecules through cross-coupling and cyclization reactions. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol boronic ester group makes it an excellent partner for palladium-catalyzed coupling with aryl halides, enabling efficient carbon-carbon bond formation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and activity-based protein profiling (ABPP) reagents.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	2-Oxo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,2-Dihydropyridine-3-Carbonitrile
CAS No.	2256755-07-2
Molecular Formula	C16H19BN2O3
Molecular Weight	298.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile; 3-Cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one; 5-BPin-3-cyano-2-pyridone; 2-Hydroxy-3-cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2256755-07-2; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Oxo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1,2-Dihydropyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.