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Potassium Trifluoro(2-Fluoro-6-Hydroxyphenyl)Borate CAS NO 2252415-10-2


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CAS No.:2252415-10-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Potassium Trifluoro(2-Fluoro-6-Hydroxyphenyl)Borate is a specialized organoboron salt, recognized as a versatile reagent and catalyst in advanced organic synthesis. Its value lies in its unique trifluoroborate moiety, which offers enhanced stability and reactivity compared to traditional boronic acids, making it a critical component for cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel fluorinated active ingredients and complex molecular scaffolds.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
  • Suzuki-Miyaura Cross-Coupling Reagent: Provides a stable and reactive partner for palladium-catalyzed carbon-carbon bond formation, crucial for constructing biaryl structures.
  • Agrochemical Synthesis: Used in the research and development of new fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
  • Material Science Research: Serves as a precursor for creating novel boron-containing polymers or organic electronic materials.
  • Catalyst Ligand Precursor: Can be utilized to generate novel ligands for transition metal catalysis in fine chemical production.
  • Academic & R&D Laboratories: A valuable tool for methodological development in synthetic organic chemistry, enabling new reaction pathways.

Basic Information

Item Detail
Product Name Potassium Trifluoro(2-Fluoro-6-Hydroxyphenyl)Borate
CAS No. 2252415-10-2
Molecular Formula C6H3BF4KO2
Molecular Weight 219.99 g/mol
Synonyms Potassium (2-Fluoro-6-hydroxyphenyl)trifluoroborate; (2-Fluoro-6-hydroxyphenyl)trifluoroborate Potassium Salt; 2-Fluoro-6-hydroxybenzenetrifluoroborate Potassium Salt; Potassium 2-Fluoro-6-hydroxybenzenetrifluoroboronate; Potassium Trifluoro(2-fluoro-6-oxidophenyl)borate(1-); K-2F-6OH-Ph-BF3; ArBF3K (where Ar = 2-fluoro-6-hydroxyphenyl)
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Quality Control

Our Potassium Trifluoro(2-Fluoro-6-Hydroxyphenyl)Borate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 2.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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