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Potassium Trifluoro(2-Fluoro-6-Hydroxyphenyl)Borate CAS NO 2252415-10-2
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CAS No.:2252415-10-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Potassium Trifluoro(2-Fluoro-6-Hydroxyphenyl)Borate is a specialized organoboron salt, recognized as a versatile reagent and catalyst in advanced organic synthesis. Its value lies in its unique trifluoroborate moiety, which offers enhanced stability and reactivity compared to traditional boronic acids, making it a critical component for cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel fluorinated active ingredients and complex molecular scaffolds.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
- Suzuki-Miyaura Cross-Coupling Reagent: Provides a stable and reactive partner for palladium-catalyzed carbon-carbon bond formation, crucial for constructing biaryl structures.
- Agrochemical Synthesis: Used in the research and development of new fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
- Material Science Research: Serves as a precursor for creating novel boron-containing polymers or organic electronic materials.
- Catalyst Ligand Precursor: Can be utilized to generate novel ligands for transition metal catalysis in fine chemical production.
- Academic & R&D Laboratories: A valuable tool for methodological development in synthetic organic chemistry, enabling new reaction pathways.
Basic Information
| Item | Detail |
|---|---|
| Product Name | Potassium Trifluoro(2-Fluoro-6-Hydroxyphenyl)Borate |
| CAS No. | 2252415-10-2 |
| Molecular Formula | C6H3BF4KO2 |
| Molecular Weight | 219.99 g/mol |
| Synonyms | Potassium (2-Fluoro-6-hydroxyphenyl)trifluoroborate; (2-Fluoro-6-hydroxyphenyl)trifluoroborate Potassium Salt; 2-Fluoro-6-hydroxybenzenetrifluoroborate Potassium Salt; Potassium 2-Fluoro-6-hydroxybenzenetrifluoroboronate; Potassium Trifluoro(2-fluoro-6-oxidophenyl)borate(1-); K-2F-6OH-Ph-BF3; ArBF3K (where Ar = 2-fluoro-6-hydroxyphenyl) |
| EINECS | Contact for details |
Quality Control
Our Potassium Trifluoro(2-Fluoro-6-Hydroxyphenyl)Borate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP manufacturing.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
| Heavy Metals | ≤ 20 ppm |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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