Description

Ch2Cooh-Peg9-Ch2Cooh is a high-purity, bifunctional polyethylene glycol derivative, precisely engineered for advanced material synthesis and bioconjugation. This compound is valued for its dual carboxylic acid termini, which provide reactive handles for creating stable linkages with amines and other functional groups under mild conditions. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and specialty polymer industries, enabling the development of PEGylated therapeutics, hydrogels, and functionalized surfaces.

Application

• Pharmaceutical PEGylation: As a linker for attaching therapeutic proteins, peptides, or small molecule drugs to polyethylene glycol chains to enhance solubility, stability, and circulation half-life.
• Bioconjugation & Cross-linking: For creating stable amide bonds with amine-containing biomolecules (e.g., antibodies, enzymes) in diagnostic assay development and targeted drug delivery systems.
• Functional Polymer Synthesis: Serving as a difunctional monomer or macromonomer for synthesizing biodegradable hydrogels, smart materials, and amphiphilic block copolymers.
• Surface Modification: For grafting hydrophilic, non-fouling PEG layers onto nanoparticles, medical devices, or biosensor surfaces to improve biocompatibility and reduce non-specific binding.
• Chemical Intermediate: Used in the multi-step synthesis of complex dendrimers, star polymers, and other advanced macromolecular architectures.

Basic Information

Product Name	Ch2Cooh-Peg9-Ch2Cooh
CAS No.	2250056-46-1
Molecular Formula	C24H44O13
Molecular Weight	564.60 g/mol
Synonyms	α,ω-Bis(carboxymethyl)nonakis(oxyethylene); PEG-9 diacetic acid; 3,6,9,12,15,18,21,24,27-Nonaoxanonatriacontanedioic acid; Bis(carboxymethyl) PEG-9; 2,2'-(Oxybis(ethane-2,1-diyl))bis(oxy))diacetic acid (PEG-9 variant); Polyethylene glycol 400 diacetic acid; HOOC-CH2-(O-CH2-CH2)9-O-CH2-COOH; Difunctional PEG-9 acid
EINECS	Contact for details

Quality Control

Our Ch2Cooh-Peg9-Ch2Cooh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, functional group content, and impurity profiles. We support compliance with relevant regulatory frameworks, and specifications can be aligned with customer-specific requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, seal under argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Acid Value (Titration)	190 - 210 mg KOH/g
Water Content (KF)	≤ 1.0%
Polyethylene Glycol (PEG) Impurity	≤ 3.0%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.