Description

1,3,2-Dioxaborolane, 2-[4-[(4-Chlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl- is a high-purity, advanced boronic ester derivative, a critical intermediate in modern synthetic chemistry. Its value lies in its role as a versatile building block for constructing complex molecules via cross-coupling reactions, enabling the development of novel materials and active pharmaceutical ingredients. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to create new functional molecules with precision.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its boronate functionality for efficient carbon-carbon bond formation.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[4-[(4-Chlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	2246937-34-6
Molecular Formula	C19H22BClO3
Molecular Weight	344.64 g/mol
Synonyms	2-(4-((4-Chlorophenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-((4-Chlorophenoxy)methyl)phenylboronic acid pinacol ester; [4-[(4-Chlorophenyl)methoxy]phenyl]boronic acid pinacol ester; (4-((4-Chlorobenzyl)oxy)phenyl)boronic acid pinacol ester; 2-[4-[(4-Chlorophenyl)methoxy]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Chlorobenzyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl ether
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-[4-[(4-Chlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.