Description

1,3,2-Dioxaborolane, 2-[2-(2-Chlorophenyl)-1-Propen-1-Yl]-4,4,5,5-Tetramethyl- is a specialized organoboron compound featuring a pinacol boronate ester group tethered to a chlorophenyl-substituted propenyl moiety. This structure makes it a valuable key synthetic intermediate for constructing complex molecules via cross-coupling reactions. It is primarily sought by pharmaceutical and agrochemical R&D teams for the development of new active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reagent: A critical building block for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those containing chlorophenyl motifs.
• Agrochemical Synthesis: Serves as a precursor in the creation of new herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is required.
• Ligand and Catalyst Development: Utilized as a starting material for synthesizing novel boron-containing ligands for metal catalysis.
• Chemical Biology Probes: Acts as a handle for bioconjugation and labeling in probe development due to its reactive boronate ester group.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[2-(2-Chlorophenyl)-1-Propen-1-Yl]-4,4,5,5-Tetramethyl-
CAS No.	2246920-03-4
Molecular Formula	C15H20BClO2
Molecular Weight	278.58 g/mol
Synonyms	2-(2-(2-Chlorophenyl)prop-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Chlorophenyl)propenyl Pinacol Boronate; 2-(2-(2-Chlorophenyl)allyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(2-Chloro-α-methylstyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E/Z)-2-[2-(2-Chlorophenyl)prop-1-en-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 2246920-03-4
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical specifications such as assay and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95.0% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.