Description

2-((4,4-Dimethylcyclohexylidene)Methyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value, advanced boronic ester intermediate crucial for modern synthetic chemistry. This compound matters because it serves as a key building block for constructing complex molecules, enabling precise carbon-carbon bond formation through cross-coupling reactions. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients, functional polymers, and electronic materials. Its unique sterically hindered cyclohexylidene structure offers distinct reactivity profiles for challenging synthetic transformations.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming biaryl and other carbon-carbon bonds in pharmaceutical intermediate synthesis.
• Pharmaceutical Research & Development: Used in the discovery and process development of novel Active Pharmaceutical Ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Serves as a key intermediate in creating new herbicides, fungicides, and insecticides with improved efficacy.
• Advanced Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a functional monomer or chain-transfer agent in the production of specialty polymers with tailored properties.
• Chemical Biology & Proteomics: Utilized as a probe or linker in bioconjugation and target identification studies.

Basic Information

Item	Details
Product Name	2-((4,4-Dimethylcyclohexylidene)Methyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2246885-43-6
Molecular Formula	C16H29BO2
Molecular Weight	264.21 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-[(4,4-dimethylcyclohexylidene)methyl]-1,3,2-dioxaborolane; (4,4-Dimethylcyclohexylidene)methylboronic acid pinacol ester; Pinacol (4,4-dimethylcyclohexylidene)methylboronate; 2-[(4,4-Dimethylcyclohexylidene)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Cyclohexanone pinacol boronate derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-((4,4-Dimethylcyclohexylidene)Methyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (¹H, ¹³C, ¹¹B), and GC to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95.0% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.