Description

4,4,5,5-Tetramethyl-2-(4-(Propylthiomethyl)Phenyl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its unique molecular architecture, which combines a protected boronic acid functionality with a propylthiomethyl linker, enabling precise cross-coupling reactions and facilitating the synthesis of complex sulfur-containing molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery and advanced material development.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific sulfur and boron-containing motifs.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular control is paramount.
• Ligand and Catalyst Development: Serves as a starting material for creating novel bidentate ligands and organoboron catalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in controlled polymerization techniques to introduce functional handles into polymer backbones.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(4-(Propylthiomethyl)Phenyl)-1,3,2-Dioxaborolane
CAS No.	2246858-23-9
Molecular Formula	C₁₆H₂₅BO₂S
Molecular Weight	292.24 g/mol
Synonyms	2-(4-((Propylthio)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[4-(propylsulfanylmethyl)phenyl]-1,3,2-dioxaborolane; Pinacol (4-(Propylthiomethyl)phenyl)boronate; (4-(Propylthiomethyl)phenyl)boronic acid pinacol ester; 4-(Propylthiomethyl)benzeneboronic acid pinacol ester; B-[4-[(Propylthio)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(4-(Propylthiomethyl)Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.