Description

1,3,2-Dioxaborolane, 2-[3-[(3-Chlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl- is a specialized organoboron compound, specifically a pinacol boronic ester derivative, valued for its role as a key synthetic intermediate. Its core value proposition lies in enabling precise carbon-carbon and carbon-heteroatom bond formation, which is critical for constructing complex molecular architectures. This high-purity building block is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing biaryl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aromatic coupling steps.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as polymers for OLEDs or organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and bioconjugation reagents due to its reactive boronic ester functionality.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[3-[(3-Chlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	2246838-42-4
Molecular Formula	C19H22BClO3
Molecular Weight	344.64 g/mol
Synonyms	2-(3-((3-Chlorophenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; [3-[(3-Chlorophenyl)methoxy]phenyl]boronic acid pinacol ester; 3-((3-Chlorobenzyl)oxy)phenylboronic acid pinacol ester; (3-((3-Chlorobenzyl)oxy)phenyl)boronic acid pinacol ester; Pinacol [3-[(3-chlorophenyl)methoxy]phenyl]boronate; Boronic acid, B-[3-[(3-chlorophenyl)methoxy]phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 1,3,2-Dioxaborolane, 2-[3-[(3-Chlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR (1H, 13C, and 11B) and Mass Spectrometry. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.