Description

2-(2-((4-Chlorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in cross-coupling reactions, enabling the precise construction of complex molecules for research and development. Pharmaceutical, agrochemical, and advanced material scientists need this reagent for creating novel active ingredients and functional materials with high efficiency and selectivity. Its well-defined structure offers reliable reactivity for Suzuki-Miyaura and other palladium-catalyzed transformations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific biphenyl or aryl-ether structures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular architecture is crucial.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological processes and target engagement.
• Polymer Chemistry: A monomer or co-monomer for synthesizing specialty polymers with tailored properties for high-performance applications.

Basic Information

Product Name	2-(2-((4-Chlorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2246833-34-9
Molecular Formula	C19H22BClO3
Molecular Weight	344.64 g/mol
Synonyms	2-(2-((4-Chlorophenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-((4-Chlorophenoxy)methyl)phenyl)boronic acid pinacol ester; 4-Chlorophenoxymethylphenylboronic acid pinacol ester; 2-[(2-{[(4-Chlorophenyl)oxy]methyl}phenyl)]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-[2-[(4-Chlorophenoxy)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 2246833-34-9
EINECS	Contact for details

Quality Control

Our 2-(2-((4-Chlorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality assurance protocols and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.