Description

1,3,2-Dioxaborolane, 2-[3-[(2,6-Difluorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl- is a high-purity, advanced boronic ester derivative designed for sophisticated organic synthesis. This compound serves as a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds under mild conditions. It is essential for researchers and process chemists in the life sciences sector who require reliable, high-quality intermediates for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its stability and reactivity to create complex molecular architectures.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs.
• Chemical Biology: Employed in the synthesis of bioconjugates and probes for studying biological pathways and protein interactions.
• Catalyst Ligand Synthesis: Serves as a starting material for the preparation of specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke organic compounds for client projects.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[3-[(2,6-Difluorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	2246827-16-5
Molecular Formula	C19H21BF2O3
Molecular Weight	346.18 g/mol
Synonyms	2-(3-((2,6-Difluorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; [3-[(2,6-Difluorophenyl)methoxy]phenyl]boronic acid pinacol ester; 3-[(2,6-Difluorobenzyl)oxy]phenylboronic acid pinacol ester; (3-((2,6-Difluorobenzyl)oxy)phenyl)boronic acid pinacol ester; PINACOL [3-[(2,6-DIFLUOROPHENYL)METHOXY]PHENYL]BORONATE; CAS 2246827-16-5
EINECS	Contact for details

Quality Control

Our production of this boronic ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Every lot is characterized using advanced analytical techniques, including NMR, HPLC, and GC, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.