Description

2-(2-Chloro-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its structural motif for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for creating complex organic semiconductors and emissive layer materials in display technologies.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Polymer and Material Science: Incorporated into polymer backbones or as a functional handle to create advanced polymers with specific electronic or mechanical properties.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	2-(2-Chloro-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2246825-67-0
Molecular Formula	C₁₃H₁₈BClO₂
Molecular Weight	252.54 g/mol
Synonyms	2-(2-Chloro-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Chloro-5-methylphenyl)boronic acid pinacol ester; 2-Chloro-5-methylbenzeneboronic acid pinacol ester; Pinacol (2-chloro-5-methylphenyl)boronate; 2-Chloro-5-methylphenylboronic acid pinacol ester; 2-Chloro-5-methylphenyl-Bpin; B-(2-Chloro-5-methylphenyl)pinacolborane; CAS 2246825-67-0
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required by the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.