Description

1,3,2-Dioxaborolane, 2-[3-[(4-Chlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl- is a high-purity, advanced boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of novel materials and active pharmaceutical ingredients. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-boronate functionalities.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for bio-conjugation and imaging applications.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[3-[(4-Chlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	2246811-63-0
Molecular Formula	C19H22BClO3
Molecular Weight	344.64 g/mol
Synonyms	2-(3-((4-Chlorophenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; [3-[(4-Chlorophenyl)methoxy]phenyl]boronic acid pinacol ester; 3-((4-Chlorobenzyl)oxy)phenylboronic acid pinacol ester; (3-((4-Chlorobenzyl)oxy)phenyl)boronic acid pinacol ester; 4-Chlorobenzyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl ether; PINACOL [3-[(4-CHLOROPHENYL)METHOXY]PHENYL]BORONATE
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H and 13C), and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent hydrolysis and maintain stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.