Description

2-(2-((3-Fluorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the stability and reactivity of the boronate group.
• Material Science: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and OFETs.
• Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new C-C bond formation strategies and library synthesis.
• Diagnostic Reagent Manufacturing: Potential use in creating fluorescent probes or molecular tags for bioimaging and diagnostic assays.

Basic Information

Item	Details
Product Name	2-(2-((3-Fluorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2246780-16-3
Molecular Formula	C19H22BFO3
Molecular Weight	328.19 g/mol
Synonyms	2-(2-((3-Fluorophenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-((3-Fluorophenoxy)methyl)phenyl)boronic acid pinacol ester; 2-[(2-{[3-Fluorophenoxy]methyl}phenyl)]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Fluoro Phenoxymethyl Phenyl Boronic Acid Pinacol Ester; 2-(2-((3-Fluorobenzyloxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (common misnomer); B-(2-((3-Fluorophenoxy)methyl)phenyl)boronic acid pinacol ester; CAS 2246780-16-3
EINECS	Contact for details

Quality Control

Our 2-(2-((3-Fluorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.