Description

4,4,5,5-Tetramethyl-2-(2-((p-Tolyloxy)Methyl)Phenyl)-1,3,2-Dioxaborolane is a sophisticated, high-purity boronic ester derivative, a critical intermediate in modern synthetic chemistry. Its value lies in its role as a versatile building block for constructing complex molecular architectures via cross-coupling reactions, offering chemists precise control and high efficiency. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the introduction of specific aromatic motifs.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for creating electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer & Material Science: Employed in the synthesis of specialty polymers, liquid crystals, and organic semiconductors with tailored electronic properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for methodology development and constructing complex organic molecules.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(2-((p-Tolyloxy)Methyl)Phenyl)-1,3,2-Dioxaborolane
CAS No.	2246777-76-2
Molecular Formula	C20H25BO3
Molecular Weight	324.22 g/mol
Synonyms	2-(2-((4-Methylphenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-[2-[(4-Methylphenoxy)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-((p-Tolyloxy)methyl)phenyl)boronic acid pinacol ester; 2-((p-Tolyloxy)methyl)phenylboronic acid pinacol ester; Pinacol [2-((4-methylphenoxy)methyl)phenyl]boronate
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(2-((p-Tolyloxy)Methyl)Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.