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1,3,2-Dioxaborolane, 2-(4-Methoxy-3-Propoxyphenyl)-4,4,5,5-Tetramethyl- CAS NO 2246765-89-7


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CAS No.:2246765-89-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,3,2-Dioxaborolane, 2-(4-Methoxy-3-Propoxyphenyl)-4,4,5,5-Tetramethyl- is a high-purity, advanced boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in providing a protected, air-stable form of a functional arylboronic acid, enabling complex cross-coupling reactions essential for pharmaceutical and material science research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecular architectures.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester precursor, fundamental in synthesizing complex biaryl structures for active pharmaceutical ingredients (APIs).
  • Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
  • Agrochemical Research: Employed in creating new active ingredients for crop protection agents by constructing specific aromatic ring systems.
  • Material Science & Organic Electronics: Serves as a monomer or building block for synthesizing conjugated polymers and small molecules used in OLEDs, OFETs, and other organic semiconductor applications.
  • Ligand and Catalyst Development: Utilized in the synthesis of novel bidentate or polydentate ligands for catalysis.
  • Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the creation of molecular probes for imaging and diagnostic applications.

Basic Information

Product Name 1,3,2-Dioxaborolane, 2-(4-Methoxy-3-Propoxyphenyl)-4,4,5,5-Tetramethyl-
CAS No. 2246765-89-7
Molecular Formula C16H25BO4
Molecular Weight 292.18 g/mol
Synonyms 4-Methoxy-3-propoxybenzeneboronic acid pinacol ester; 2-(4-Methoxy-3-propoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; (4-Methoxy-3-propoxy-phenyl)boronic acid pinacol ester; Pinacol (4-Methoxy-3-propoxy-phenyl)boronate; 3-Propoxy-4-methoxyphenylboronic acid pinacol ester; AR-Boronates (4-Methoxy-3-propoxy)
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Quality Control

Our 1,3,2-Dioxaborolane, 2-(4-Methoxy-3-Propoxyphenyl)-4,4,5,5-Tetramethyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥97.0% (Area %)
Purity (GC) ≥98.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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