Description

2-(2-((4-Bromophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity organoboron building block, specifically a pinacol boronic ester, critical for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or aryl-heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Useful in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs (Contract Research Organizations) serving the global life sciences industry.

Basic Information

Product Name	2-(2-((4-Bromophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2246758-17-6
Molecular Formula	C19H22BBrO3
Molecular Weight	389.09 g/mol
Synonyms	[2-[[(4-Bromophenoxy)methyl]phenyl]boronic acid pinacol ester; 2-[(4-Bromophenoxy)methyl]phenylboronic acid pinacol ester; (2-((4-Bromophenoxy)methyl)phenyl)boronic acid pinacol ester; 4-Bromophenoxymethylphenylboronic acid pinacol ester; Pinacol [2-((4-bromophenoxy)methyl)phenyl]boronate; 2-(2-((4-Bromophenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 2246758-17-6
EINECS	Contact for details

Quality Control

Our 2-(2-((4-Bromophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.