Description

1,3,2-Dioxaborolane, 2-[4-[(3,4-Dichlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl- is a high-purity, protected boronic ester derivative, a critical intermediate in modern synthetic organic chemistry. Its value lies in providing a stable, reactive handle for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl systems. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific biaryl structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable organoboron reagent for palladium-catalyzed carbon-carbon bond formation to create complex molecular architectures.
• Material Science Research: Intermediate in the development of organic electronic materials, such as OLEDs and semiconductors, where precise conjugation is needed.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Fine Chemical Production: Enables the scalable synthesis of specialty chemicals and complex organic molecules for various industrial applications.

Basic Information

Item	Detail
Product Name	1,3,2-Dioxaborolane, 2-[4-[(3,4-Dichlorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	2246740-41-8
Molecular Formula	C19H21BCl2O3
Molecular Weight	379.08 g/mol
Synonyms	4-[(3,4-Dichlorophenoxy)methyl]phenylboronic acid pinacol ester; [4-[(3,4-Dichlorophenoxy)methyl]phenyl]boronic acid pinacol ester; 2-[4-[(3,4-Dichlorophenoxy)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-((3,4-Dichlorophenoxy)methyl)phenyl)boronic acid pinacol ester; PINACOL [4-[(3,4-DICHLOROPHENOXY)METHYL]PHENYL]BORONATE
EINECS	Contact for details

Quality Control

Every batch of our 1,3,2-Dioxaborolane derivative is produced under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which typically include identity confirmation by NMR and FT-IR, purity assessment by HPLC, and control of residual solvents. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.