Description

2-(4-((2-Bromophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a versatile boronic ester reagent for constructing biaryl and heterobiaryl structures, which are core motifs in many pharmaceuticals and organic electronic materials.
• Pharmaceutical Intermediate Synthesis: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research & Development: Used in creating new active ingredients for herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, light-emitting diodes (OLEDs), and other functional materials requiring precise aromatic coupling.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules or for creating molecular probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis organizations (CSOs) and CDMOs producing specialized, high-value compounds for clients.

Basic Information

Product Name	2-(4-((2-Bromophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2246676-65-1
Molecular Formula	C19H22BBrO3
Molecular Weight	389.09 g/mol
Synonyms	4-[(2-Bromophenoxy)methyl]phenylboronic acid pinacol ester; 2-Bromo-4'-(pinacolatoboron)benzyl phenyl ether; [4-[(2-Bromophenoxy)methyl]phenyl]boronic acid pinacol ester; (4-((2-Bromophenoxy)methyl)phenyl)boronic acid pinacol ester; 2-Bromophenoxy-methyl-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; PINACOL 4-[(2-BROMOPHENOXY)METHYL]BENZENEBORONATE
EINECS	Contact for details

Quality Control

Every batch of our 2-(4-((2-Bromophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.