Description

2-(3-((4-Bromo-2-Chlorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those containing biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Research: A versatile reagent for academic and industrial research in palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel ligands and organometallic catalysts.
• Custom Synthesis: Employed in contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	2-(3-((4-Bromo-2-Chlorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2246646-61-5
Molecular Formula	C19H21BBrClO3
Molecular Weight	426.54 g/mol
Synonyms	3-((4-Bromo-2-chlorophenoxy)methyl)phenylboronic acid pinacol ester; (3-((4-Bromo-2-chlorophenoxy)methyl)phenyl)boronic acid pinacol ester; 4-Bromo-2-chloro-1-((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)benzene; 2-(3-((4-Bromo-2-chlorophenoxy)methyl)phenyl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; B-(3-((4-Bromo-2-chlorophenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 2246646-61-5
EINECS	Contact for details

Quality Control

Every batch of our 2-(3-((4-Bromo-2-Chlorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) specifying purity (typically ≥95% by HPLC), identity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.