Description

1,3,2-Dioxaborolane, 2-[4-[(2-Fluorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl- is a high-purity, organoboron building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules, particularly in pharmaceutical research and materials science, due to its reactive boronic ester functionality. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester partner for palladium-catalyzed carbon-carbon bond formation, enabling the construction of complex organic architectures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Materials Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugation reagents for diagnostic and research applications.
• Process Chemistry & Scale-up: Suitable for optimization and scaling in pilot plants and commercial manufacturing of fine chemicals.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[4-[(2-Fluorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	2246642-41-9
Molecular Formula	C19H22BFO3
Molecular Weight	328.19 g/mol
Synonyms	2-(4-((2-Fluorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[4-[(2-fluorophenyl)methoxy]phenyl]-1,3,2-dioxaborolane; 2-Fluoro-4'-(pinacolboryl)benzyloxybenzene; (4-((2-Fluorobenzyl)oxy)phenyl)boronic acid pinacol ester; 2-[4-[(2-Fluorophenyl)methoxy]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.