Description

1,3,2-Dioxaborolane, 2-[2-[(4-Fluorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl- is a high-value, protected boronic ester derivative, serving as a crucial synthetic intermediate in modern organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation, a fundamental step in constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the introduction of specific fluorinated aromatic motifs.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor in the synthesis of electron-transport materials or host materials for high-performance display and lighting technologies.
• Ligand and Catalyst Development: Serves as a starting material for creating novel bidentate or tridentate ligands used in homogeneous catalysis.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functional materials with tailored electronic or optical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Item	Details
Product Name	1,3,2-Dioxaborolane, 2-[2-[(4-Fluorophenyl)Methoxy]Phenyl]-4,4,5,5-Tetramethyl-
CAS No.	2246638-38-8
Molecular Formula	C19H22BFO3
Molecular Weight	328.19 g/mol
Synonyms	2-(2-((4-Fluorobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; [2-[(4-Fluorophenyl)methoxy]phenyl]boronic acid pinacol ester; 4-Fluorobenzyloxy-substituted phenylboronic acid pinacol ester; (2-((4-Fluorobenzyl)oxy)phenyl)boronic acid pinacol ester; PINACOL (2-((4-FLUOROBENZYL)OXY)PHENYL)BORONATE
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane derivative is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. Due to its hygroscopic and easily oxidized nature, the container should be allowed to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.