Description

2-(2-((4-Methoxyphenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile and stable organoboron reagent, essential for constructing complex molecular architectures via cross-coupling reactions. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key precursor for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those containing complex aromatic or heteroaromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) for advanced material applications.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors due to its reactive boronate functional group.
• Process Chemistry & Scale-up: Provides a reliable and scalable intermediate for pilot plant and commercial manufacturing of fine chemicals.

Basic Information

Product Name	2-(2-((4-Methoxyphenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2246614-75-3
Molecular Formula	C20H25BO4
Molecular Weight	340.22 g/mol
Synonyms	2-(2-((4-Methoxyphenoxy)methyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-((4-Methoxyphenoxy)methyl)phenyl)boronic acid pinacol ester; 2-[(2-{[(4-Methoxyphenyl)oxy]methyl}phenyl)]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-[(2-{[(4-Methoxyphenoxy)methyl]phenyl})]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-[2-[[(4-methoxyphenoxy)methyl]phenyl]]-, pinacol ester; [2-((4-Methoxyphenoxy)methyl)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(2-((4-Methoxyphenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.