Description

2-(2-((4-Bromo-2-Fluorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used to construct novel herbicide and fungicide candidates through palladium-catalyzed coupling reactions.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation in drug discovery.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-(2-((4-Bromo-2-Fluorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2246573-09-9
Molecular Formula	C19H21BBrFO3
Molecular Weight	422.08 g/mol
Synonyms	4-Bromo-2-fluoro-1-((2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)benzene; 2-(2-((4-Bromo-2-fluorophenoxy)methyl)phenyl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; (2-((4-Bromo-2-fluorophenoxy)methyl)phenyl)boronic acid pinacol ester; 4-Bromo-2-fluorophenyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl ether; B-(2-((4-Bromo-2-fluorophenoxy)methyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(2-((4-Bromo-2-Fluorophenoxy)Methyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air or moisture must be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.