Description

2-(Bromodifluoromethyl)-2,4,4,5,5-Pentafluoro-1,3-Oxathiolane CAS NO 2244085-08-1 is a high-value, multi-fluorinated heterocyclic building block designed for advanced chemical synthesis. This compound is critical for introducing the unique and highly reactive bromodifluoromethyl group into target molecules, enabling the development of novel materials with tailored properties. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries for applications in fluorination chemistry and the creation of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and pesticides where fluorine atoms improve efficacy and environmental profile.
• Fluorinated Polymer & Material Science: Serves as a monomer or functionalization agent for creating specialty polymers, coatings, and electronic materials with enhanced chemical resistance, thermal stability, and low surface energy.
• Ligand & Catalyst Development: Employed in the synthesis of novel fluorinated ligands and organocatalysts for asymmetric synthesis and other advanced catalytic processes.
• Fluorine-18 Radiochemistry: A potential precursor for the synthesis of positron emission tomography (PET) imaging agents, leveraging its reactive bromine atom for late-stage radiofluorination strategies.
• Organic Synthesis Building Block: Enables diverse transformations, including nucleophilic substitutions and cross-coupling reactions, to construct complex, fluorinated organic molecules for research and development.

Basic Information

Product Name	2-(Bromodifluoromethyl)-2,4,4,5,5-Pentafluoro-1,3-Oxathiolane
CAS No.	2244085-08-1
Molecular Formula	C4BrF7OS
Molecular Weight	296.99 g/mol
Synonyms	2-(Bromodifluoromethyl)-2,4,4,5,5-pentafluoro-1,3-oxathiolane; 1,3-Oxathiolane, 2-(bromodifluoromethyl)-2,4,4,5,5-pentafluoro-; Bromodifluoromethyl pentafluoro oxathiolane; 2,4,4,5,5-Pentafluoro-2-(bromodifluoromethyl)-1,3-oxathiolane; Pentafluoroxathiolane bromodifluoromethyl derivative; Fluorinated oxathiolane bromo compound
EINECS	Contact for details

Quality Control

Our 2-(Bromodifluoromethyl)-2,4,4,5,5-Pentafluoro-1,3-Oxathiolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F), GC-MS, and HPLC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to minimize volatility and degradation. Due to its hygroscopic and highly volatile nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use and allowed to equilibrate to room temperature before opening to prevent moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.5%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.9 g/mL
Refractive Index (n20D)	~1.38

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.