Description

Piperidine, 4-(Dimethoxymethyl)-1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-value, multi-functional boronic ester derivative of piperidine, designed for advanced synthetic chemistry. This compound matters as a critical building block in modern pharmaceutical and agrochemical research, enabling efficient Suzuki-Miyaura cross-coupling reactions to construct complex carbon-carbon bonds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the boronic ester functionality for structural diversification.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Cross-Coupling Reactions: An essential reagent for Suzuki-Miyaura cross-coupling, facilitating the efficient and selective formation of biaryl and other complex molecular architectures.
• Medicinal Chemistry Library Construction: Enables high-throughput parallel synthesis for creating diverse compound libraries for biological screening and hit-to-lead optimization.
• Ligand and Catalyst Development: Utilized in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis applications.

Basic Information

Item	Details
Product Name	Piperidine, 4-(Dimethoxymethyl)-1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	2242744-56-3
Molecular Formula	C20H32BNO4
Molecular Weight	361.29 g/mol
Synonyms	1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-4-(dimethoxymethyl)piperidine; 4-(Dimethoxymethyl)-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine; 4-(Dimethoxymethyl)-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperidine; Pinacol [4-(4-(dimethoxymethyl)piperidin-1-yl)phenyl]boronate; [4-(4-(Dimethoxymethyl)piperidin-1-yl)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Piperidine, 4-(Dimethoxymethyl)-1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO compliant production for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.