Description

(3-(Methoxy-D3)Phenyl)Boronic Acid is a deuterated aromatic boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in the strategic incorporation of deuterium atoms, which can significantly alter the metabolic profile and stability of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of deuterated active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in Suzuki-Miyaura cross-coupling reactions for the synthesis of deuterated drug candidates, potentially improving pharmacokinetics and patent life.
• Deuterated API Development: Used in the research and production of Active Pharmaceutical Ingredients (APIs) where deuterium substitution is employed for metabolic stabilization (deuterium kinetic isotope effect).
• Agrochemical Research: Serves as a precursor for creating novel, deuterated pesticides and herbicides with potentially enhanced environmental persistence or efficacy.
• Material Science: Employed in the synthesis of deuterated organic electronic materials, liquid crystals, and polymers for specialized research applications.
• Isotope Labeling: Acts as a versatile reagent for introducing deuterium labels into complex organic frameworks for mechanistic studies, metabolic tracing, or analytical standards.
• Chemical Biology Probes: Useful in constructing deuterium-labeled probes for studying biological processes and protein-ligand interactions via techniques like NMR or mass spectrometry.

Basic Information

Product Name	(3-(Methoxy-D3)Phenyl)Boronic Acid
CAS No.	2241867-05-8
Molecular Formula	C7H6D3BO3
Molecular Weight	153.97 g/mol (approx.)
Synonyms	(3-(Trideuteriomethoxy)phenyl)boronic acid; (3-Methoxy-d3-phenyl)boronic acid; 3-(Methoxy-d3)benzeneboronic acid; B-[3-(Methoxy-d3)phenyl]boronic acid; m-(Methoxy-d3)phenylboronic acid; 3-(CD3O)C6H4B(OH)2; (3-Methoxyl-d3-phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our (3-(Methoxy-D3)Phenyl)Boronic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C), HPLC, and mass spectrometry, to confirm identity, chemical purity, and isotopic enrichment. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity. Ideal storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Isotopic Purity (D-enrichment)	≥98 atom % D
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.