Description

6-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole is a high-value, advanced pharmaceutical intermediate featuring a versatile indazole core functionalized with a pinacol boronate ester group. This compound is critical for modern drug discovery, serving as a key building block in the synthesis of complex molecules through cross-coupling reactions. It is primarily sought after by research institutions and pharmaceutical companies engaged in developing novel therapeutics, particularly in oncology and CNS disorders.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal reagent for constructing carbon-carbon bonds in the synthesis of complex drug candidates and agrochemicals.
• Pharmaceutical Intermediate: Used in the research and development of targeted therapies, especially kinase inhibitors and other small molecule drugs.
• Organic Synthesis Building Block: Enables the modular construction of diverse indazole-containing compounds for material science and chemical biology research.
• Agrochemical Research: Employed in the development of new active ingredients with specific biological activity.
• Ligand Synthesis: Useful for creating novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole
CAS No.	2241721-69-5
Molecular Formula	C₁₄H₁₉BN₂O₂
Molecular Weight	258.13 g/mol
Synonyms	6-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methyl-1H-indazole; 6-Methyl-7-(pinacolatoboryl)-1H-indazole; 6-Methyl-7-boronic acid pinacol ester indazole; 1H-Indazole, 6-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2241721-69-5; 6-Methyl-7-(pinacolboron)-1H-indazole
EINECS	Contact for details

Quality Control

Our production of 6-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with client specifications and industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.