Description

Benzyl 2-(4-(Methoxycarbonyl)Phenyl)-4-Oxopiperidine-1-Carboxylate CAS NO 2238811-87-3 is a high-purity, advanced pharmaceutical intermediate characterized by its piperidinone core and benzyl-protected carboxylate group. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Synthesis: Used in the construction of piperidine-based frameworks common in protease inhibitor development.
• Kinase Inhibitor Development: A valuable building block for creating potential kinase inhibitors targeting various disease pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical entities.

Basic Information

Product Name	Benzyl 2-(4-(Methoxycarbonyl)Phenyl)-4-Oxopiperidine-1-Carboxylate
CAS No.	2238811-87-3
Molecular Formula	C21H21NO5
Molecular Weight	367.40 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-2-[4-(methoxycarbonyl)phenyl]-4-piperidinone; Benzyl 2-(4-(methoxycarbonyl)phenyl)-4-oxo-1-piperidinecarboxylate; 4-Oxo-2-[4-(methoxycarbonyl)phenyl]-1-piperidinecarboxylic acid benzyl ester; 1-CBz-2-(4-COOMe-phenyl)-4-piperidinone; 2-(4-Methoxycarbonylphenyl)-4-oxopiperidine-1-carboxylic acid benzyl ester; 4-Oxopiperidine-1,2-dicarboxylic acid 1-benzyl ester 2-[4-(methyl ester)]
EINECS	Contact for details

Quality Control

Our Benzyl 2-(4-(Methoxycarbonyl)Phenyl)-4-Oxopiperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong alkalis and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.