Description

[1,1'-Biphenyl]-4-Carbonitrile, 4'-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Naphthalenyl]- is a high-value, multi-functional organic building block that combines a biphenyl-naphthalene core with both nitrile and boronic ester functional groups. This unique structure makes it a critical intermediate in modern synthetic chemistry, particularly for constructing complex molecules via cross-coupling reactions. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging its structural complexity for enhanced efficacy.
• Organic Electronic Materials: Serves as a precursor for organic semiconductors, hole-transport materials, and emitters in OLED (Organic Light-Emitting Diode) devices.
• Ligand and Catalyst Development: The nitrile and boronate ester groups allow for the creation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Incorporated into high-performance polymers to modify thermal stability, mechanical properties, and optical characteristics.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new synthetic methodologies and material properties.

Basic Information

Product Name	[1,1'-Biphenyl]-4-Carbonitrile, 4'-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Naphthalenyl]-
CAS No.	2234895-19-1
Molecular Formula	C29H26BNO2
Molecular Weight	431.34 g/mol
Synonyms	4'-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-yl)-[1,1'-biphenyl]-4-carbonitrile; 1-Naphthaleneboronic acid, 4'-(4-cyanobiphenyl-4-yl)-, 1,3,2-dioxaborolane ester; 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-yl)biphenyl-4-carbonitrile; Biphenyl-naphthalene boronic ester nitrile; Biphenyl nitrile boronate ester; (4'-Cyanobiphenyl-4-yl)naphthalene-1-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of [1,1'-Biphenyl]-4-Carbonitrile, 4'-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-Naphthalenyl]- is manufactured under strict quality management systems. Our products undergo rigorous quality testing including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency, meeting the stringent requirements for advanced synthetic intermediates. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the product should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.