Description

2,2,2-Trifluoroacetic Acid is a highly versatile and potent fluorinated organic acid. It serves as a critical reagent and solvent in advanced organic synthesis, particularly valued for its strong acidity and ability to facilitate difficult reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• As a powerful solvent and catalyst in peptide synthesis and oligonucleotide deprotection.
• As a key reaction medium and acidifying agent in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• In the production of agrochemicals, including herbicides and pesticides, where its trifluoromethyl group is integral.
• As a mobile phase modifier in High-Performance Liquid Chromatography (HPLC) for analyzing basic compounds.
• For the manufacture of dyes, pigments, and specialty polymers requiring fluorinated building blocks.
• In academic and industrial R&D for exploring new fluorination methodologies and organofluorine chemistry.

Basic Information

Product Name	2,2,2-Trifluoroacetic Acid
CAS No.	2231675-04-8
Molecular Formula	C2HF3O2
Molecular Weight	114.02 g/mol
Synonyms	Trifluoroacetic Acid; TFA; Perfluoroacetic Acid; 2,2,2-Trifluoroethanoic Acid; Trifluoroethanoic Acid; CF3COOH; NSC 77384
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoroacetic Acid is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat and incompatible materials such as strong bases and oxidizing agents. Due to its hygroscopic and highly volatile nature, containers should be kept tightly sealed and under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.5%
Water Content (KF)	≤ 0.1%
Residue on Ignition	≤ 0.01%
Chloride (Cl)	≤ 10 ppm
Sulfate (SO4)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.