Description

Benzonitrile, 4-[3-[(Acetyloxy)Methyl]-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]- is a high-value, multi-functional chemical intermediate featuring a boronic ester pinacol group and a benzonitrile core. This compound is specifically engineered for advanced organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is an essential building block for research and development in the pharmaceutical, agrochemical, and materials science industries, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biphenyl or substituted aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aromatic frameworks.
• Liquid Crystal & OLED Material Production: Serves as a building block for creating advanced organic electronic materials and liquid crystal display (LCD) components.
• Polymer & Resin Modification: Incorporated into specialty polymers to alter physical properties, thermal stability, or introduce functional sites for further reaction.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new catalytic processes and synthesizing novel organic molecules.
• Ligand & Catalyst Development: Used in the preparation of sophisticated ligands for metal catalysis and organocatalysts.

Basic Information

Item	Details
Product Name	Benzonitrile, 4-[3-[(Acetyloxy)Methyl]-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]-
CAS No.	2227126-13-6
Molecular Formula	C22H24BNO5
Molecular Weight	393.24 g/mol
Synonyms	4-[3-(Acetoxymethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]benzonitrile; 2-(4-(4-Cyanophenoxy)-2-(hydroxymethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane acetate; 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(acetoxymethyl)phenoxy)benzonitrile; Boronic acid, B-[4-(4-cyanophenoxy)-2-(acetoxymethyl)phenyl]-, pinacol ester; (4-(4-Cyanophenoxy)-2-(acetoxymethyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our Benzonitrile, 4-[3-[(Acetyloxy)Methyl]-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]- is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR (¹H & ¹³C), and GC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.