Description

3-Bromofuran-2,5-diboronic acid pinacol ester is a high-value, multi-functional boronic ester derivative crucial for advanced organic synthesis. This compound serves as a versatile building block in cross-coupling reactions, enabling the precise construction of complex heterocyclic frameworks. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing carbon-carbon bonds to create complex biaryl and heteroaryl structures in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the synthesis of potential drug candidates, particularly those containing functionalized furan cores.
• Agrochemical Research: Serves as a precursor in developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs.
• Chemical Biology & Probe Development: Useful for creating molecular probes and labeled compounds for biological target identification and study.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, multi-functional boronic acid derivatives.

Basic Information

Product Name	3-Bromofuran-2,5-diboronic Acid Pinacol Ester
CAS No.	2225873-46-9
Molecular Formula	C16H21BBrO6
Molecular Weight	383.05 g/mol
Synonyms	2,5-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-bromofuran; 3-Bromo-2,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan; 3-Bromofuran-2,5-diyldiboronic Acid Bis(pinacol) Ester; 3-Bromo-2,5-furandiyldiboronic Acid Pinacol Ester; 3-Bromofuran-2,5-diboronic Acid Bis(1,1,1',1'-tetramethylenyl) Ester
EINECS	Contact for details

Quality Control

Our 3-Bromofuran-2,5-diboronic acid pinacol ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and potentially air/moisture-sensitive nature. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.