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N,n-Bis(4-Methoxyphenyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine CAS NO 2225806-07-3
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CAS No.:2225806-07-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
N,n-Bis(4-Methoxyphenyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex carbon-carbon bonds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional organic materials.
Application
- Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in oncology and CNS therapeutic areas.
- Agrochemical Research: Used in creating novel active ingredients for crop protection products through efficient aryl-aryl coupling.
- Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport or emissive layer materials in display and lighting technologies.
- Polymer Chemistry: Enables the synthesis of conjugated polymers and specialty materials with tailored electronic properties.
- Academic & R&D Laboratories: Essential reagent for methodological development and exploratory synthesis in organic chemistry.
- Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
Basic Information
| Product Name | N,n-Bis(4-Methoxyphenyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine |
| CAS No. | 2225806-07-3 |
| Molecular Formula | C30H32BNO4 |
| Molecular Weight | 481.39 g/mol |
| Synonyms | 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-bis(4-methoxyphenyl)naphthalen-2-amine; N,N-Bis(4-methoxyphenyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-amine; 2-Naphthalenamine, N,N-bis(4-methoxyphenyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Boronic acid, B-[6-[bis(4-methoxyphenyl)amino]-2-naphthalenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; 2225806-07-3; Aryl boronate ester intermediate; Suzuki coupling reagent. |
| EINECS | Contact for details |
Quality Control
Our N,n-Bis(4-Methoxyphenyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry inert atmosphere to protect the moisture-sensitive boronate ester functionality and prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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