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N,n-Bis(4-Methoxyphenyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine CAS NO 2225806-07-3


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CAS No.:2225806-07-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N,n-Bis(4-Methoxyphenyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex carbon-carbon bonds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional organic materials.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in oncology and CNS therapeutic areas.
  • Agrochemical Research: Used in creating novel active ingredients for crop protection products through efficient aryl-aryl coupling.
  • Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport or emissive layer materials in display and lighting technologies.
  • Polymer Chemistry: Enables the synthesis of conjugated polymers and specialty materials with tailored electronic properties.
  • Academic & R&D Laboratories: Essential reagent for methodological development and exploratory synthesis in organic chemistry.
  • Ligand Synthesis: Used in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name N,n-Bis(4-Methoxyphenyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine
CAS No. 2225806-07-3
Molecular Formula C30H32BNO4
Molecular Weight 481.39 g/mol
Synonyms 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-bis(4-methoxyphenyl)naphthalen-2-amine; N,N-Bis(4-methoxyphenyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-amine; 2-Naphthalenamine, N,N-bis(4-methoxyphenyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Boronic acid, B-[6-[bis(4-methoxyphenyl)amino]-2-naphthalenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; 2225806-07-3; Aryl boronate ester intermediate; Suzuki coupling reagent.
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Quality Control

Our N,n-Bis(4-Methoxyphenyl)-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalen-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry inert atmosphere to protect the moisture-sensitive boronate ester functionality and prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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