Description

3-(Tetrahydro-2H-Pyran-4-Yl)Phenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial organoboron reagent for forming carbon-carbon bonds between aromatic rings, a fundamental transformation in medicinal chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Material Science Research: Acts as a building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and affinity tags for studying biological systems.

Basic Information

Product Name	3-(Tetrahydro-2H-Pyran-4-Yl)Phenylboronic Acid
CAS No.	2225175-24-4
Molecular Formula	C11H15BO3
Molecular Weight	206.05 g/mol
Synonyms	[3-(Oxan-4-yl)phenyl]boronic acid; 3-(Tetrahydro-2H-pyran-4-yl)benzeneboronic acid; 3-(Tetrahydro-2H-pyran-4-yl)phenylboronic acid; 3-(4-Tetrahydropyranyl)phenylboronic Acid; B-[3-(Tetrahydro-2H-pyran-4-yl)phenyl]boronic acid; 3-(THP-4-yl)phenylboronic acid; 3-(Oxan-4-yl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-(Tetrahydro-2H-Pyran-4-Yl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.