Description

6-(tert-Butyl)Pyridine-3-Boronic Acid Pinacol Ester is a high-value organoboron building block, specifically a pyridine-substituted boronic ester. Its core value proposition lies in enabling efficient and selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form new carbon-carbon bonds, introducing the tert-butyl pyridine moiety into target molecules.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and bioconjugates where the boronic ester group allows for further functionalization.
• Catalyst Ligand Synthesis: Can be utilized to prepare novel nitrogen-containing ligands for transition metal catalysis.

Basic Information

Item	Details
Product Name	6-(tert-Butyl)Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	2223047-95-6
Molecular Formula	C15H24BNO2
Molecular Weight	261.17 g/mol
Synonyms	6-tert-Butylpyridine-3-boronic acid pinacol ester; (6-(tert-Butyl)pyridin-3-yl)boronic acid pinacol ester; 3-Borono-6-tert-butylpyridine pinacol ester; 6-tert-Butyl-3-pyridineboronic acid pinacol ester; 6-tert-Butyl-3-pyridinylboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-tert-butylpyridine; 2-tert-Butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 6-(tert-Butyl)Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B), HPLC, and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards required for GMP intermediates and research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry inert atmosphere to protect the moisture-sensitive boronic ester functionality and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.