Description

2-Amino-3-Methylphenylboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, facilitating handling and storage while remaining a key reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides through cross-coupling methodologies.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs and organic semiconductors.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Ligand and Catalyst Preparation: Utilized in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Fine Chemical Production: Employed in the manufacture of complex dyes, pigments, and other specialty fine chemicals requiring precise molecular construction.

Basic Information

Item	Details
Product Name	2-Amino-3-Methylphenylboronic Acid Pinacol Ester
CAS No.	2223047-06-9
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	2-Amino-3-methylbenzeneboronic acid pinacol ester; (2-Amino-3-methylphenyl)boronic acid pinacol ester; 2-Methyl-6-aminophenylboronic acid pinacol ester; Pinacol (2-amino-3-methylphenyl)boronate; B-(2-Amino-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methyl-2-aminophenylboronic acid pinacol ester; 2-Amino-m-tolylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.