Description

Methyl 6-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinate is a high-value, multi-functional chemical building block essential for modern synthetic chemistry. Its core value lies in the unique combination of a picolinate ester and a pinacol boronate ester, enabling precise carbon-carbon bond formation and functional group transformations. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and oncology drug discovery.
• Agrochemical Synthesis: Used to create complex heterocyclic structures found in modern herbicides, fungicides, and insecticides, contributing to crop protection solutions.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing sophisticated chelating ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and emissive compounds for OLEDs.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 6-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinate
CAS No.	2223040-39-7
Molecular Formula	C15H22BNO4
Molecular Weight	291.15 g/mol
Synonyms	Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methylpicolinate; 6-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinic Acid Methyl Ester; 4-Borono-6-methylpicolinic Acid Methyl Ester Pinacol Ester; 2-Pyridinecarboxylic Acid, 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methyl-, Methyl Ester; Methyl 4-BPin-6-methylpicolinate
EINECS	Contact for details

Quality Control

Our Methyl 6-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.