Description

2-Chloro-4-Bromo-5-Methylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and specialty chemical manufacturing.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Employed in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Utilized in the development of organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for studying biological systems.

Basic Information

Item	Details
Product Name	2-Chloro-4-Bromo-5-Methylphenylboronic Acid Pinacol Ester
CAS No.	2223037-58-7
Molecular Formula	C13H17BBrClO2
Molecular Weight	330.44 g/mol
Synonyms	2-Chloro-4-bromo-5-methylbenzeneboronic acid pinacol ester; (2-Chloro-4-bromo-5-methylphenyl)boronic acid pinacol ester; 4-Bromo-2-chloro-5-methylbenzeneboronic acid pinacol ester; Pinacol (2-chloro-4-bromo-5-methylphenyl)boronate; B-(2-Chloro-4-bromo-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 2223037-58-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Bromo-5-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.