Description

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine is a high-value, advanced pharmaceutical intermediate and versatile building block in modern synthetic chemistry. This compound is critical for enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental to constructing complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development programs.
• Suzuki-Miyaura Cross-Coupling: Serves as a crucial boronic ester reagent for forming carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the design and synthesis of novel herbicides, fungicides, and insecticides with improved efficacy.
• Materials Science: Building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and tools for studying biological systems and protein functions.
• Ligand Synthesis: Intermediate for the preparation of sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine
CAS No.	2223033-00-7
Molecular Formula	C15H20BNO2
Molecular Weight	257.14 g/mol
Synonyms	6,7-Dihydro-5H-cyclopenta[b]pyridin-3-ylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydrocyclopenta[b]pyridine; 3-Pinacolatoboryl-6,7-dihydro-5H-cyclopenta[b]pyridine; Cyclopenta[b]pyridine-3-boronic acid pinacol ester; 3-Boronic acid, 6,7-dihydro-5H-cyclopenta[b]pyridine-, pinacol ester; 2223033-00-7
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6,7-dihydro-5H-cyclopenta[b]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for critical synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.