Description

1,3,2-Dioxaborolane-2-Butanoic Acid, 4,4,5,5-Tetramethyl-, Methyl Ester is a high-purity, advanced boronic ester building block critical for modern synthetic chemistry. This compound matters as a versatile and stable intermediate, enabling precise carbon-carbon bond formation and functional group transformations under mild conditions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality reagents for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific boronic ester functionalities.
• Materials Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other functional polymers.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new catalytic cycles and synthetic methodologies.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts.
• Peptide Modification & Bioconjugation: Facilitates the site-specific labeling and modification of biomolecules.

Basic Information

Product Name	1,3,2-Dioxaborolane-2-Butanoic Acid, 4,4,5,5-Tetramethyl-, Methyl Ester
CAS No.	2222868-64-4
Molecular Formula	C11H21BO4
Molecular Weight	228.10 g/mol
Synonyms	4,4,5,5-Tetramethyl-2-(2-methoxy-2-oxoethyl)-1,3,2-dioxaborolane; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate; 2-(2-Methoxy-2-oxoethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Methyl 3-(pinacolatoboryl)propanoate; 3-(Pinacolatoboryl)propionic Acid Methyl Ester; Pinacol 3-(Methoxycarbonyl)ethylboronate; Propanoic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane-2-Butanoic Acid, 4,4,5,5-Tetramethyl-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and lot-to-lot consistency. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.