Description

2-(4-Phenoxyphenyl)-1,3,2-Dioxaborinane is a specialized organoboron compound, specifically a cyclic boronic ester, serving as a valuable synthetic intermediate. Its core value proposition lies in its utility as a protected boronic acid derivative, offering enhanced stability and handling characteristics compared to its free acid form for advanced cross-coupling reactions. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity building blocks for Suzuki-Miyaura and other palladium-catalyzed couplings.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing biaryl motifs common in many drug molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate complex aromatic structures.
• Materials Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs, where precise molecular architecture is critical.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel boron-containing ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors that leverage boronate ester chemistry for detection and binding applications.

Basic Information

Product Name	2-(4-Phenoxyphenyl)-1,3,2-Dioxaborinane
CAS No.	2222401-82-1
Molecular Formula	C16H15BO3
Molecular Weight	266.10 g/mol
Synonyms	4-Phenoxyphenylboronic acid 1,3-propanediol ester; 2-(4-Phenoxyphenyl)-1,3,2-dioxaborinane; 4-Phenoxyphenyl-1,3,2-dioxaborinane; (4-Phenoxyphenyl)boronic acid cyclic ester with 1,3-propanediol; 4-Phenoxybenzeneboronic acid 1,3-propanediol ester; B-(4-Phenoxyphenyl)-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 2-(4-Phenoxyphenyl)-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.