Description

Florfenicol-D3 is a deuterium-labeled internal standard of the broad-spectrum veterinary antibiotic, Florfenicol, specifically designed for high-precision analytical applications. This stable isotope-labeled compound is essential for ensuring accurate quantification and method validation in complex biological matrices. It is primarily used by research scientists and quality control laboratories in the pharmaceutical, veterinary medicine, and food safety sectors for advanced mass spectrometry-based analyses.

Application

• Quantitative Mass Spectrometry (LC-MS/MS, GC-MS): Serves as a critical internal standard for the precise and accurate quantification of Florfenicol residues in tissues, plasma, milk, and feed.
• Pharmacokinetic and Metabolism Studies: Enables reliable tracking of drug absorption, distribution, metabolism, and excretion (ADME) in veterinary research.
• Regulatory Compliance Testing: Supports method development and validation for monitoring Florfenicol residues to ensure compliance with food safety regulations (e.g., FDA, EU MRLs).
• Biomedical Research: Used as a tracer in mechanistic studies to investigate the biological pathways and environmental fate of Florfenicol.
• Quality Control in Reference Material Production: Employed in the calibration and certification of certified reference materials (CRMs) for Florfenicol.

Basic Information

Product Name	Florfenicol-D3
CAS No.	2213400-85-0
Molecular Formula	C12H11D3Cl2FNO4S
Molecular Weight	358.24 g/mol (approximate)
Synonyms	Florfenicol-d3; [D3]-Florfenicol; 2,2-Dichloro-N-[(1R,2S)-3-(deuteriomethoxy)-1-(3,5-dichloro-4-fluorophenyl)-2-hydroxypropyl]acetamide; Deuterated Florfenicol; Florfenicol Internal Standard; Florfenicol IS; (1R,2S)-3-(Methoxy-d3)-1-(3,5-dichloro-4-fluorophenyl)-2-[(dichloroacetyl)amino]propan-1-ol
EINECS	Contact for details

Quality Control

Our Florfenicol-D3 is manufactured under strict quality protocols to ensure the highest isotopic purity and chemical integrity required for analytical applications. Each batch undergoes comprehensive analysis, including HPLC, NMR, and mass spectrometry, to confirm identity, chemical purity, and isotopic enrichment. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.