Description

1-Isobutyl-3,5-Dimethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole is a high-value, synthetically versatile organoboron building block. This compound is essential for facilitating key carbon-carbon and carbon-heteroatom bond-forming reactions in advanced chemical synthesis. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for constructing biaryl and heterobiaryl scaffolds prevalent in pharmaceutical and material science.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those containing pyrazole cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and emissive materials for electronic devices.
• Chemical Biology & Probe Development: Utilized for creating molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, functionalized heterocyclic boronic esters.

Basic Information

Product Name	1-Isobutyl-3,5-Dimethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	2205068-12-6
Molecular Formula	C15H27BN2O2
Molecular Weight	278.20 g/mol
Synonyms	1-Isobutyl-3,5-dimethyl-1H-pyrazole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isobutyl-3,5-dimethyl-1H-pyrazole; 1H-Pyrazole-4-boronic acid, 1-(2-methylpropyl)-3,5-dimethyl-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; Pyrazole boronic ester pinacol; 1-Isobutyl-3,5-dimethylpyrazole-4-boronic acid pinacol ester; CAS 2205068-12-6
EINECS	Contact for details

Quality Control

Our 1-Isobutyl-3,5-Dimethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.