Description

Benzoic Acid, 2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is a high-value, multifunctional chemical building block featuring a protected boronic ester group. This compound is essential for facilitating complex carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern synthetic chemistry. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring specific aryl-aryl linkages.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Serves as a monomer or building block for creating novel polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological systems.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.

Basic Information

Product Name	Benzoic Acid, 2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester
CAS No.	2201133-24-4
Molecular Formula	C14H18BClO4
Molecular Weight	296.55 g/mol
Synonyms	Methyl 2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid Methyl Ester; 3-Boronic acid, 2-chlorobenzoic acid methyl ester, pinacol ester; (2-Chloro-3-(methoxycarbonyl)phenyl)boronic acid pinacol ester; Pinacol (2-chloro-3-methoxycarbonylphenyl)boronate; CAS 2201133-24-4
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.