Description

4,4,5,5-Tetramethyl-2-(Naphtho[2,3-B]Benzofuran-1-Yl)-1,3,2-Dioxaborolane is a sophisticated, high-purity boronic ester derivative designed for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for developing new active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures prevalent in pharmaceutical candidates.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly for targets requiring extended conjugated systems.
• Agrochemical Synthesis: Employed in creating advanced herbicide and fungicide molecules with enhanced efficacy and selectivity.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for electron-transport materials and emitting layer components in display and lighting technologies.
• Polymer and Material Science: Facilitates the synthesis of specialty polymers and organic semiconductors with tailored electronic properties.
• Ligand and Catalyst Development: Useful for constructing novel ligand frameworks for transition metal catalysis.
• Chemical Biology Probes: Serves as a handle for bioconjugation and the development of molecular probes for imaging and diagnostic applications.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(Naphtho[2,3-B]Benzofuran-1-Yl)-1,3,2-Dioxaborolane
CAS No.	2189692-41-7
Molecular Formula	C24H23BO3
Molecular Weight	370.25 g/mol
Synonyms	1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)naphtho[2,3-b]benzofuran; Naphtho[2,3-b]benzofuran-1-ylboronic acid pinacol ester; 1-(Naphtho[2,3-b]benzofuran-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Naphtho[2,3-b]benzofuranyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Naphthobenzofuranyl pinacol boronate; Naphtho[2,3-b]benzofuran-1-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 4,4,5,5-Tetramethyl-2-(Naphtho[2,3-B]Benzofuran-1-Yl)-1,3,2-Dioxaborolane is manufactured and tested under strict quality management systems. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry, to ensure the material meets the exacting standards required for research and process chemistry. A Certificate of Analysis (COA) is supplied with each shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.