Description

tert-Butyl cis-3-{2-[(4-Methylbenzenesulfonyl)Oxy]Ethoxycyclobutane-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclobutane ring structure. This compound is critical for enabling complex synthetic routes in modern medicinal chemistry, offering a versatile building block for drug discovery and development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly those targeting complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a critical reagent for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Synthetic Organic Chemistry: Employed in academic and industrial R&D for constructing complex, strained ring systems and exploring new chemical transformations.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds under cGMP conditions.

Basic Information

Item	Details
Product Name	tert-Butyl cis-3-{2-[(4-Methylbenzenesulfonyl)Oxy]Ethoxycyclobutane-1-Carboxylate
CAS No.	2173637-23-3
Molecular Formula	C19H28O6S
Molecular Weight	384.49 g/mol
Synonyms	tert-Butyl 3-[2-(p-toluenesulfonyloxy)ethoxy]cyclobutane-1-carboxylate; tert-Butyl 3-(2-((tosyl)oxy)ethoxy)cyclobutane-1-carboxylate; cis-tert-Butyl 3-(2-((4-methylphenyl)sulfonyl)oxy)ethoxy)cyclobutane-1-carboxylate; 1-Cyclobutanecarboxylic acid, 3-[2-[(4-methylphenyl)sulfonyl]oxy]ethoxy]-, 1,1-dimethylethyl ester, cis-; Tosyloxyethoxy Cyclobutane Carboxylate tert-Butyl Ester; CAS 2173637-23-3
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl cis-3-{2-[(4-Methylbenzenesulfonyl)Oxy]Ethoxycyclobutane-1-Carboxylate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate production. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.