Description

Bis(Trifluoroacetic Acid) is a highly reactive and potent fluorinated organic acid derivative, serving as a critical reagent and building block in advanced synthetic chemistry. Its value lies in its ability to introduce trifluoroacetyl groups and act as a strong acid catalyst in demanding, moisture-sensitive reactions where conventional acids are unsuitable. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, particularly for developing active pharmaceutical ingredients (APIs), fluorinated polymers, and complex organic molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for introducing the trifluoroacetyl protecting group in peptide and nucleoside chemistry, and in the synthesis of complex drug molecules.
• Agrochemical Production: Used in the manufacture of advanced, fluorinated pesticides and herbicides to enhance their biological activity and environmental stability.
• Catalyst & Reagent: Functions as a strong, volatile acid catalyst in esterification, condensation, and cleavage reactions, especially useful in reactions requiring subsequent easy removal.
• Polymer & Material Science: Employed in the synthesis of fluorinated polymers, coatings, and specialty materials that require high thermal stability and chemical resistance.
• Organic Synthesis Building Block: Serves as a versatile precursor for generating other trifluoromethyl-containing compounds and complex molecular architectures in research and development.
• Analytical Chemistry: May be used as a derivatization agent or a component in mobile phases for chromatographic analysis of specific compound classes.

Basic Information

Product Name	Bis(Trifluoroacetic Acid)
CAS No.	2173083-55-9
Molecular Formula	C4HF6O4 (or (CF3CO)2O related structure)
Molecular Weight	Contact for details
Synonyms	Bis(Trifluoroacetic) Acid; Trifluoroacetic Anhydride related compound; Perfluoropropionic Anhydride derivative; TFA Dimer; Hexafluorodiacetic Acid; 1,1,1,3,3,3-Hexafluoro-2,2-propanediol di(trifluoroacetate) (possible structure); Bis(trifluoroacetyl) oxide derivative
EINECS	Contact for details

Quality Control

Our Bis(Trifluoroacetic Acid) is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including assay (HPLC), identity confirmation (IR, NMR), and impurity profiling, to ensure it meets the high-purity standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) documenting purity, physical properties, and safety data is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials such as strong bases, amines, and oxidizing agents. Due to its nature as a strong acid/organic solvent and highly volatile compound, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (HPLC)	≤ 1.0% (total)
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.